Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus
نویسندگان
چکیده
1Genetic Skin Disease Group, and 2Department of Immunofluorescence, St. John’s Institute of Dermatology, The Guy’s, King’s College and St. Thomas’ Hospitals’ Medical School, St. Thomas’ Hospital, London, United Kingdom. 3Department of Dermatology, Fukushima Medical University School of Medicine, Fukushima, Japan. 4Department of Dermatology, The Churchill Hospital, Oxford, United Kingdom. 5Lupus Research Unit, Rayne Institute, Immunology Department, St. Thomas’ Hospital, London, United Kingdom.
منابع مشابه
Autoantibodies to extracellular matrix protein 1 in lichen sclerosus.
BACKGROUND Lichen sclerosus is a common acquired inflammatory disorder of skin and mucous membranes. The aetiology is unknown, although HLA-subtype susceptibility and high rates of other autoimmune disorders suggest that autoantibodies to specific mucocutaneous antigens are involved. The clinicopathological similarities between lichen sclerosus and lipoid proteinosis, which results from mutatio...
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